Epidermal growth factor signaling (EGFR) regulates cell fate, survival and proliferation and is evolutionarily conserved. Aberrant EGFR signaling is implicated in many diseases including cancer. In Drosophila, EGFR signaling plays an important role during development. A microarray based approach to identify previously unknown targets of EGFR signaling in the wing imaginal disc was employed. RNA samples from wing discs expressing constitutively active or dominant negative forms of dEGFR were compared using oligonucleotide arrays and candidate genes were verified using in situ hybridizations.Current study intends to characterize one of these novel targets, CG4096, using reverse genetics. Knockdown of CG4096 showed wing defects. Further examination, including overexpression analysis is required to determine whether CG4096 play a role in EGFR signaling.